By Avram Goldstein
Content material: medicinal drugs and the mind. Neurotransmitters : the brain's personal medicinal drugs -- Receptors : locks for the addictive keys -- Addictive habit -- ache and enjoyment -- The seesaw mind : "highs" and diversifications -- Are addicts born or made? the medicine and the addicts. Nicotine -- Alcohol and similar medications -- Heroin, morphine, and different opiates -- Cocaine and amphetamines -- hashish (Marijuana) -- Caffeine -- Hallucinogens. medicines and society. Prevention : simply say no? -- Treating dependancy, fighting relapse -- 3 classes from the road -- 3 classes from in another country -- Prohibition vs. legalization : a fake dichotomy -- New options for rational drug coverage
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Extra resources for Addiction : from biology to drug policy
But because the brain is a chemical organ, brain chemistry is responsible for the finely regulated and coordinated functioning of both the hardware and the software. Thus, even psychologic disorders must arise ultimately through Neurotransmitters: The Brain's Own Drugs \ 21 chemical changes. It is not a question of psychology versus biology; on the contrary, in the final analysis psychology is biology. Chemical Transmission The origins of our modern understanding of chemical transmission in the brain can be traced to the middle 1800s, in France.
Here was this peptide, 17 amino acids long, the blueprint for which had been hidden in the genes for countless millions of years—and my colleagues and I had cracked the secret! Moreover, we had not only discovered a new opioid peptide neurotransmitter; as we soon realized, we had found one that was hundreds of times more potent than morphine or any opioid peptide then known. I named it dynorphin from the Greek prefix meaning power (as in dynamic) and the suffix-orphin (as in beta-endorphin). Where in the Brain?
Unable to wait until evening, the craving nagging at him relentlessly, he quit work and rushed home. He is missing important business, but no business is as important as what he is about to do. Sitting on a soft easy chair, he places a pellet of crack cocaine in the bowl of a little pipe. He trembles with anticipation as he lights it and inhales deeply. " An overwhelming sense of alertness, power, deep satisfaction, almost-orgasmic pleasure sweeps over him. A few hours later, he is still at it, using up his entire $200 supply of crack cocaine, needing more and more of it to sustain the euphoria.
Addiction : from biology to drug policy by Avram Goldstein